Prognostic value of a computer-aided diagnosis system involving bone scans among men treated with docetaxel for metastatic castration-resistant prostate cancer

Table 2 Univariate and multivariate analysis of overall survival after the administration of docetaxel

Variables at docetaxel induction	Univariate analysis				Multivariate analysis
	p value	Hazard ratio	95.0 % CI		p value	Hazard ratio	95.0 % CI
	p value	Hazard ratio	Lower	Upper	p value	Hazard ratio	Lower	Upper
PSA (≥56.8 ng/mL vs <56.8)	0.115	1.991	0.845	4.693	0.894	0.929	0.317	2.729
Age(>73 vs ≤73)	0.623	0.810	0.349	1.879	0.944	0.964	0.343	2.704
Liver mets (yes vs no)	0.239	1.825	0.670	4.969	0.026	3.681	1.166	11.616
Local therapy (yes vs no)	0.137	0.218	0.029	1.624	0.206	0.213	0.019	2.339
Hb (<11.7 g/dL vs ≥11.7)	0.072	0.457	0.194	1.072	0.887	1.073	0.404	2.850
LDH (>225 IU/L vs ≤225)	0.045	2.385	1.019	5.578	0.078	2.500	0.903	6.915
Alb (<3.9 g/dL vs ≥3.9)	0.001	5.965	1.987	17.908	0.020	3.776	1.238	11.516
PSADT (≤1.4 months vs >1.4)	0.123	1.971	0.832	4.668	0.888	1.075	0.392	2.948
BSI (>1 % vs ≤1 %)	0.035	2.673	1.072	6.661	0.037	3.356	1.078	10.453

PSA prostate-specific antigen, PSADT PSA doubling time, Hb hemoglobin, LDH lactate dehydrogenase, Alb albumin, BSI bone scan index, Liver mets liver metastasis
The normal ranges of Hb, LDH and Alb were 11.3–14.5 g/dL, 116–199 IU/L and 4.2–5.4 g/dL, respectively

ISSN: 1471-2407