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Table 2 Incidence of colorectal cancer in relation to a 5 unit change in anthropometric measure: Hazard ratios and 95 % CI

From: Change in weight and waist circumference and risk of colorectal cancer: results from the Melbourne Collaborative Cohort Study

  Model 1 a Model 2 b
  HR 95 % CI p-value c HR 95 % CI p-value c
Colorectal (C18-20) d       
Waist change (per 5 cm) 1.00 [0.93, 1.08] 0.924 1.02 [0.95, 1.10] 0.542
Weight change (per 5 kg) 0.92 [0.84, 1.02] 0.107 0.93 [0.85, 1.02] 0.147
Hips change (per 5 cm) 0.98 [0.90, 1.07] 0.654 1.01 [0.92, 1.10] 0.905
Colon (C18) e       
Waist change (per 5 cm) 1.01 (0.93, 1.10) 0.777 1.03 (0.95, 1.12) 0.444
Weight change (per 5 kg) 0.94 (0.84, 1.05) 0.278 0.95 (0.86, 1.05) 0.327
Hips change (per 5 cm) 0.96 (0.87, 1.07) 0.484 0.99 (0.89, 1.10) 0.840
Rectal (C19,C20) f       
Waist change (per 5 cm) 0.98 (0.86, 1.11) 0.763 1.00 (0.88, 1.13) 0.977
Weight change (per 5 kg) 0.88 (0.73, 1.06) 0.190 0.89 (0.75, 1.06) 0.191
Hips change (per 5 cm) 1.03 (0.88, 1.20) 0.747 1.05 (0.90, 1.22) 0.529
  1. aModel 1: Estimates adjusted for sex and country of birth
  2. bModel 2: Estimates adjusted as in model 1, as well as quintile of socioeconomic status, family history of any cancer, body size at baseline, cumulative smoking status, and physical activity and Mediterranean diet score at baseline and wave 2
  3. c P-values from Cox proportional hazard model
  4. d373 colorectal cancer cases in 186,329 person-years at risk
  5. Incidence rate of colorectal cancer = 2.00 per 1,000 person-years (95% CI = 1.81, 2.22)
  6. e272 colon cancer cases (C18); Incidence rate = 1.46 per 1,000 person-years (95% CI = 1.30, 1.64)
  7. f101 rectal cancer caases (C19,20); Incidence rate = 0.54 per 1,000 person-years (95% CI = 0.45, 0.66)