Skip to main content

Table 2 CTC detection and expression of the genes in CD45-depleted peripheral blood at levels higher than those of healthy donors

From: CXCR4-SDF-1 interaction potentially mediates trafficking of circulating tumor cells in primary breast cancer

Gene

Number of positive samples

% of positive samples

KRT19

20

13.6

TWIST1 a

4

2.7

SNAIL1

0

0.0

SLUG a

17

11.6

ZEB1

0

0.0

CTC_EP only

17

11.6

CTC_EMT only

17

11.6

CTC co-expressing both markersb

3

2.0

Any CTC

37

25.2

  1. aIn one patient sample, there was overexpression of two EMT-inducing TF gene transcripts (SLUG and TWIST1)
  2. bIn one sample there was co-overexpression of KRT19 and SLUG, while in other two samples there was co-overexpression of KRT19 and TWIST1