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Table 2 Multivariate cox regression survival analysis

From: Expression and promotor hypermethylation of miR-34a in the various histological subtypes of ovarian cancer

   PFS OS
   HR CI 95 % p value HR CI 95 % p value
miR-34a expressionc high 0.549 [0.31–0.969] 0.039a 0.509 [0.293–0.883] 0.016a
low 1      
FIGO stage late 1.646 [0.7–3.871] 0.253 2.058 [0.895–4.727] 0.089
  early 1      
Age >62.3 1.69 [1.017–2.813] 0.043a 2.565 [1.571–4.189] <0.0001b
  <62.3 1      
Residual disease RD > 0 1.97 [1.057–3.674] 0.033a 2.565 [1.571–4.189] 0.001b
  RD = 0 1      
Hystology d 0.998 [0.773–1.288] 0.987 1.132 [0.886–1.446] 0.321
   Serous cancers  
   PFS OS
   HR CI 95 % p value HR CI 95 % p value
miR-34a expressionc high 0.509 [0.227–1.143] 0.102 0.389 [0.173–0.876] 0.022a
low 1      
FIGO stage late 2.866 [0.77–10.662] 0.043 2.858 [0.748–10.915] 0.125
  early 1      
Age >62.3 2.304 [1.082–4.905] 0.032 2.925 [1.386–6.174] 0.005
  <62.3 1      
Residual disease RD > 0 1.194 [0.456–3.128] 0.718 1.080 [0.397–2.938] 0.879
  RD = 0 1      
  1. asignificant at the 0.05 level (2-tailed). bsignificant at the 0.01 level (2-tailed). carbitrary units normalized to TBP, cut off = 20th centile (0.14)
  2. dserous VS endometrioid VS mucinous VS clear cell