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Table 3 Relationship between differentiation, depth of invasion and lymphovascular invasion with macroscopic type, size and histology

From: A nomogram for predicting the likelihood of lymph node metastasis in early gastric patients

Clinicopathologic-al features Differentiation p Lymphovascular invasion p Depth of invasion P
Differentiated (%) Undifferentiated (%) Absent (%) Present (%) Mucosa (%) Submucosa (%)
Macroscopic type    0.001    <0.001    <0.001
I/II 189 (47.7) 207 (52.3)   372 (93.9) 24 (6.1)   266 (67.2) 130 (32.8)  
III/Mixed 66 (32.8) 135 (67.2)   165 (82.1) 36 (17.9)   69 (34.3) 132 (65.7)  
Size (cm)    <0.001    <0.001    <0.001
<2.0 149 (51.0) 143 (49.0)   278 (95.2) 14 (4.8)   191 (65.4) 101 (34.6)  
≥2.0 106 (34.8) 199 (65.2)   259 (84.9) 46 (15.1)   144 (47.2) 161 (52.8)  
Histology    <0.001    0.255    0.724
Adenocarcinoma 241 (55.4) 194 (44.6)   395 (90.8) 40 (9.2)   246 (56.6) 189 (43.4)  
Other typesa 14 (8.6) 148 (91.4)   142 (87.7) 20 (45.4)   89 (54.9) 73 (45.1)  
  1. Other typesa: signet-ring cell carcinoma, mucinous adenocarcinoma, etc
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