|
Reference
|
Intervention
|
Pts. (n)
|
chemo-naïve (%)
|
PFS6 mo (%)
|
PFS (weeks)
|
|---|
|
Brandes (2004) [23]
|
BCNU ± re-resection
|
40
|
100
|
17.5
|
13.3
|
|
Fine (2003) [25]
|
BCNU + thalidomide
|
38
|
50
|
27
|
14.9
|
|
Prados (2004) [26]
|
BCNU + TMZ (single dose)
|
38
|
89.5
|
21
|
11
|
|
Brandes (2004) [24]
|
BCNU + irinotecan
|
42
|
0
|
30.3
|
17
|
|
Yung (2000) [46]
|
TMZ (5/28) vs. procarbazine
|
112
|
35
|
21 vs. 8
|
12.4
|
|
Brada (2001) [47]
|
TMZ (5/28)
|
128
|
29
|
18
|
8
|
|
Brandes (2002) [48]
|
TMZ (5/28)
|
42
|
0
|
24
|
11.7
|
|
Chang (2004) [49]
|
TMZ (5/28)
|
142
|
56
|
18
|
10
|
|
Wick (2007) [50]
|
TMZ (7/14)
|
64
|
36
|
43.8
|
24
|
|
Perry (2010) [51]
|
TMZ (continuous)
|
91
|
NR
|
23.9
|
7–15
|
|
Kappelle (2001) [52]
|
PCV
|
63
|
68.2
|
29
|
13
|
|
Wong (1999) [53]
|
historical controls
|
225
|
NR
|
15
|
9
|
- ND not determined, NR not reported
