|
Variable
| |
Hazard ratioa
|
95 % CI
|
p-value
|
|---|
|
Age at 1st diagnosis
|
per year
|
1.03
|
1.00–1.05
|
0.04
|
|
EOR
|
CR vs. PR
|
0.76
|
0.41–1.40
|
0.64
|
|
TMZ at 1st diagnosis
|
yes vs. no
|
0.32
|
0.15–0.71
|
0.005
|
|
Therapies other than BCNU at tumor recurrence
|
yes vs. no
|
0.56
|
0.30–1.02
|
0.06
|
|
MGMT promoter methylation
|
yes vs. no
|
0.89
|
0.51–1.53
|
0.66
|
|
BCNU
|
yes vs. no
|
0.48
|
0.26–0.89
|
0.02
|
- aA hazard ratio <1 (>1) indicates an effect in favor of the first (second) group
- CI confidence interval, EOR extent of resection, CR complete resection, PR partial resection/biopsy
