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Table 1 Patient characteristics and outcome for stage I & II colon cancer patients

From: Isolated tumor cells in stage I & II colon cancer patients are associated with significantly worse disease-free and overall survival

Patient characteristics Total N = 74 ITC N = 23 No ITC N = 51 p
Age (Years) 70.6 ± 11.4 69.3 ± 10.2 71.2 ± 11.9 0.494 A)
Gender Male 39 (52.7 %) 13 (56.5 %) 26 (51.0 %) 0.659 B)
  Female 35 (47.3 %) 10 (43.5 %) 25 (49.0 %)  
Tumor localisation Colon caecum 12 (16.2 %) 1 (4.3 %) 11 (21.6 %) 0.084 B)
  Ascending colon 16 (21.6 %) 5 (21.7 %) 11 (21.6 %)  
  Transverse colon 13 (17.6 %) 4 (17.4 %) 9 (17.6 %)  
  Descending colon 7 (9.5 %) 5 (21.7 %) 2 (3.9 %)  
  Rectosigmoid colon 26 (35.1 %) 8 (34.8 %) 18 (35.3 %)  
T-stage I 7 (9.5 %) 0 (0.0 %) 7 (13.7 %) 0.264 B)
  II 21 (28.4 %) 7 (30.4 %) 14 (27.5 %)  
  III 42 (56.8 %) 14 (60.9 %) 28 (54.9 %)  
  IV 4 (5.4 %) 2 (8.7 %) 2 (3.9 %)  
Grading I 1 (1.4 %) 0 (0.0 %) 1 (2.0 %) 0.792 B)
  II 47 (63.5 %) 15 (65.2 %) 32 (62.7 %)  
  III 26 (35.1 %) 8 (34.8 %) 18 (35.3 %)  
Lymphovascular No 63 (85.1 %) 17 (73.9 %) 46 (90.2 %) 0.091 C)
invasion Yes 11 (14.9 %) 6 (26.1 %) 5 ( 9.8 %)  
Preoperative CEA <5 μg/l 59 (79.7 %) 16 (69.6 %) 43 (84.3 %) 0.167 C)
levels ≥5 μg/l 15 (20.3 %) 7 (30.4 %) 8 (15.7 %)  
TotalLNn (n) 28.6 ± 11.7 27.7 ± 11.5 29.0 ± 11.9 0.668 A)
SLNn (n) 5.8 ± 3.4 6.0 ± 3.5 5.6 ± 3.4 0.685 A)
NSLNn (n) 22.9 ± 11.6 21.7 ± 10.6 23.4 ± 12.1 0.565 A)
Adjuvant therapy No 65 (87.8 %) 17 (73.9 %) 48 (94.1 %) 0.025 C)
  Yes 9 (12.2 %) 6 (26.1 %) 3 (5.9 %)  
Recurrence No 71 ( 95.9 %) 21 (91.3 %) 50 ( 98.0 %) 0.254 C)
  Yes 3 (4.1 %) 2 (8.7 %) 1 (2.0 %)  
  Yes: liver 1 (1.4 %) 0 (0.0 %) 1 (2.0 %)  
  Yes: lung 2 (2.7 %) 2 (8.7 %) 0 (0.0 %)  
Death No 58 (78.4 %) 16 (69.6 %) 42 (82.4 %) 0.239 C)
  Yes 16 (21.6 %) 7 (30.4 %) 9 (17.6 %)  
  1. n (%); mean ± standard deviation
  2. A) t-Test, B) Chi-squared test, C) Mid-p test