Distinct genomic and epigenomic features demarcate hypomethylated blocks in colon cancer

BMC Cancer

Table 2 Enrichment of chromatin modification enzymes among the most discriminating TF motifs and their interacting partners

Classification	Top 20		Top 25		Top 40		Top 50
Classification	OR	P-Value	OR	P-Value	OR	P-Value	OR	P-Value
Boundary-Inside	1.66	2.8e-9	1.57	6.1e-8	1.48	7.5e-7	1.46	7.8e-7
Boundary-Outside	1.61	3.0e-8	1.53	3.5e-7	1.50	2.4e-7	1.45	1.4e-6
Boundary-Promoter	1.64	7.6e-9	1.56	1.2e-7	1.44	3.9e-6	1.45	1.1e-6

Odds ratio (OR) and Fisher’s Exact test P-value for a chromatin modification enzyme enrichment test using the most discriminating (Top 20, 25, 40 or 50) TF binding site motifs for each classification task (as described in Table 1)

ISSN: 1471-2407