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Table 4 The cross-neutralization pattern of immunized mice sera after different L-asparaginase administration, IgG-response

From: Comparative immunogenicity and structural analysis of epitopes of different bacterial L-asparaginases

Antigen for immunization GMT/p GMT, 95 % CI
EcA WsA YpA RrA EwA
EcA GMT   2.2 (0.2–19.2) 2.6 (0.2–38.4) 6.9 (0.3–184.0) 6.6 (0.2–176.2)
p   0.935 0.875 0.413 0.432
WsA GMT 52.3 (2.8–979.2)   6.9 (0.3–184.0) 5.7 (0.3–115.3) 10.5 (0.7–149.6)
p 0.029   0.437 0.521 0.277
YpA GMT 659.8 (178.9–2433.6) 362.4 (77.0–1705.7)   165.7 (3.3–8296.3) 50.0 (50.0–50.0)
p <0.001 <0.001   <0.001 0.003
RrA GMT 4.7 (0.0–663.9) No response 125.0 (125.0–125.0)   7.1 (0.2–257.2)
p 0.475 0.002   0.284
EwA GMT 148.7 (85.6–258.0) No response 7.1 (0.2–257.2) 8.9 (0.2–514.8)  
p <0.001 0.201 0.135