Table 3 Hazard Ratios (HR) and 95 % Confidence Intervals (CI) of cancer mortality by quartiles of biomarkers and z-score

 No of Cases/Total

62/672

54/638

79/630

92/630

 Age-adjusted

1.0 (ref)

0.95 (0.66-1.37)

1.48 (1.06-2.07)

2.09 (1.52-2.89)

0.01

 Multivariable^a

1.0 (ref)

0.93 (0.65-1.34)

1.38 (0.99-1.93)

1.88 (1.36-2.62)

0.04

 Multivariable^b

1.0 (ref)

0.87 (0.60-1.25)

1.20 (0.85-1.68)

1.39 (0.98-1.97)

0.42

 No of Cases/Total

61/639

73/643

75/645

78/643

 Age-adjusted

1.0 (ref)

1.18 (0.84-1.66)

1.37 (0.97-1.92)

1.65 (1.18-2.31)

0.02

 Multivariable^a

1.0 (ref)

1.13 (0.80-1.59)

1.25 (0.88-1.75)

1.40 (0.99-1.99)

0.12

 Multivariable^b

1.0 (ref)

1.10 (0.78-1.55)

1.12 (0.79-1.59)

1.15 (0.81-1.64)

0.43

 No of Cases/Total

54/642

65/643

77/643

91/642

 Multivariable^b

1.0 (ref)

1.12 (0.78-1.61)

1.30 (0.91-1.86)

1.48 (1.03-2.14)

0.09