|
Variables
|
Low-risk groupa
|
High-risk groupb
|
cHRsc, (95 % CI), P
|
aHRsd (95 % CI), P
|
|---|
|
No.
|
%
|
No.
|
%
|
Low-risk group (ref.) vs. High-risk group
|
Low-risk group (ref.) vs. High-risk group
|
|---|
|
OPC
|
575
|
76.5
|
177
|
23.5
| | |
|
Smoking
| | | | | | |
|
Ever
|
325
|
56.5
|
104
|
58.8
|
1.4 (0.5–3.3), 0.722
|
1.4 (0.6–3.4), 0.787
|
|
Never
|
250
|
43.5
|
73
|
41.2
|
18.9 (1.3–330.2), 0.032
|
20.0 (1.2–327.0), 0.028
|
|
Alcohol
| | | | | | |
|
Ever
|
421
|
73.2
|
128
|
72.3
|
1.3 (0.3–3.7), 0.823
|
1.4 (0.5–3.8), 0.822
|
|
Never
|
154
|
26.8
|
49
|
27.7
|
1.9 (0.3–17.2), 0.887
|
1.8 (0.2–16.1), 0.867
|
|
Non-OPC
|
614
|
79.0
|
163
|
21.0
| | |
|
Smoking
| | | | | | |
|
Ever
|
455
|
74.1
|
125
|
76.7
|
2.1 (1.1–4.2), 0.013
|
2.3 (1.2–4.4), 0.011
|
|
Never
|
159
|
25.9
|
38
|
23.3
|
0.2 (0.1–1.4), 0.346
|
0.1 (0.0–1.2), 0.323
|
|
Alcohol
| | | | | | |
|
Ever
|
426
|
69.4
|
124
|
76.1
|
2.3 (1.1–3.9), 0.022
|
2.2 (1.2–4.1), 0.019
|
|
Never
|
188
|
30.6
|
39
|
23.9
|
0.5 (0.2–4.3), 0.798
|
0.6 (0.1–4.1), 0.801
|
-
aLow-risk group: 0–2 variant genotypes
-
bHigh-risk group: 3–4 variant genotypes
-
cCrude HRs
-
dHRs were adjusted for age, sex, ethnicity, smoking, alcohol, index cancer stage, and treatment
