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Table 2 (A) List of deregulated miRNAs identified in tonsillar cancers. These miRNAs demonstrate a two-fold change from normal tonsillar tissue. (B) ΔΔG free energy value, which can be used to evaluate target site accessibility. This value was determine using the PITA algorithm ( for the first 789 bp 3’UTR of PDCD4

From: Regulation of the tumour suppressor PDCD4 by miR-499 and miR-21 in oropharyngeal cancers

microRNA Position ΔGduplex ΔGopen ΔG
miR-21 241 −10.8 −8.1 −2.69
miR-499 466 −9.5 −7.91 −1.58
miR-499 532 −17.6 −16.02 −1.57
miR-499 17 −15 −21.04 6.04