Features | Number of total cases | BRCA1 mutation (%) | BRCA2 mutation (%) | Overall mutation (%) | P-value |
---|---|---|---|---|---|
Total | 133 | 18 (13.5) | 13 (9.8) | 31 (23.3) | Â |
Age at onset | Â | Â | Â | Â | Â |
 ≤40 years | 51 | 11 (21.6) | 6 (11.8) | 17 (33.3) | 0.031 |
 >40 years | 82 | 7 (8.5) | 7 (8.5) | 14 (17.1) | |
Number of breast cancer cases in a family | Â | Â | Â | Â | Â |
 ≤2 | 99 | 12 (12.1) | 8 (8.1) | 20 (20.2) | 0.148 |
 >2 | 34 | 6 (17.6) | 5 (14.7) | 11 (32.4) | |
With a family history of ovarian cancer | Â | Â | Â | Â | Â |
 Yes | 16 | 6 (37.5) | 2 (12.5) | 8 (50.0) | 0.012 |
 No | 117 | 12 (10.3) | 11 (9.4) | 23 (19.7) | |
Bilateral breast cancer | Â | Â | Â | Â | Â |
 Yes | 15 | 3 (20) | 3 (20) | 6 (40) | 0.115 |
 No | 118 | 15 (12.7) | 10 (8.5) | 25 (21.2) |