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Table 2 Mesothelioma-derived cell lines used in this study

From: HOX transcription factors are potential targets and markers in malignant mesothelioma

Cell line

Source

IC50 HXR9 (μM)

Ref

Met-5a

Normal mesothelium cells from pleural fluid

98

[34]

NCI-H28

Pleural effusion

18

ATCC

MSTO-211H

Biphasic mesothelioma (fibroblast morphology)

28

[35]

NCI-H2052

Pleural effusion (epithelial morphology)

45

ATCC

NCI-H226

Squamous carcinoma; mesothelioma (epithelial morphology). This cell line was derived from non-small cell lung cancer, although it was subsequently found to have a number of mesothelioma-related properties, including the expression of mesothelin.

107

ATCC, [36]