Skip to main content


Fig. 3 | BMC Cancer

Fig. 3

From: The MYCN-HMGA2-CDKN2A pathway in non-small cell lung carcinoma—differences in histological subtypes

Fig. 3

Associations between gene expression and patient outcome. mRNA fold change values dichotomized to high (green) or low (blue) expression based on the median expression level. High expression of MYCN mRNA had a significantly worse prognosis compared to lower expression levels in all tumour samples (a, p = 0.029) and in a subset of squamous cell carcinomas (b, p = 0.044). Lower expression of both MYCN and HMGA2 (co-expressed) had a significantly better prognosis compared to the other alternatives (c, p = 0.040)

Back to article page