Table 2 Foetal and placental parameters in Walker tumour-bearing rats and ascitic fluid-injected rats fed either a control or leucine-rich diet

Foetal resorption per dam

0_.900_±0_.314

3_.300±0_.538*

2_.500±0_.562*

0_.889±0_.309

1_.600±0_.499

1_.700±0_.473

P = 0.0321

P = 0.0043

n.s.

Foetal weight (g)

3.92 ± 0.07

2.73 ± 0.20*

2.61 ± 0.05*

3.65 ± 0.06

2.85 ± 0.08*

2.96 ± 0.09*

n.s.

P < 0.0001

n.s.

Placenta weight (g)

0.48 ± 0.01

0.53 ± 0.02

0.42 ± 0.02

0.52 ± 0.03

0.52 ± 0.01

0.50 ± 0.02

n.s.

n.s.

n.s.

Placental protein content (μg/mg)

7.38 ± 0.48

3.81 ± 0.29*

4.70 ± 0.34*

7.14 ± 0.28

6.87 ± 0.56

6.37 ± 0.67

P = 0.0043

P = 0.0002

n.s.

Placental DNA (μg/mg)

0.46 ± 0.02

0.38 ± 0.02*

0.38 ± 0.02*

0.46 ± 0.03

0.49 ± 0.02

0.43 ± 0.04

n.s.

P = 0.0052

n.s.

Placental protein/DNA ratio^a

16.8 ± 1.2

11.5 ± 0.9*

14.2 ± 1.5

17.3 ± 1.1

15.4 ± 1.5

17.3 ± 2.5

P = 0.0212

P = 0.0311

n.s.