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Table 3 Incidence of different types of cancer and measured hazard ratios by multivariate Cox proportional hazards regression analysis for study cohorts

From: Cancer risk in East Asian patients associated with acquired haemolytic anaemia: a nationwide population-based cohort study

Cancer type

Liver

Lung

Colorectal

Lymphatic and haematopoietic tissue

Breast

Others

 

HR (95 % CI)

HR (95 % CI)

HR (95 % CI)

HR (95 % CI)

HR (95 % CI)

HR (95 % CI)

Comparison cohort

ref

ref

ref

ref

ref

ref

AHA cohort

1.23(0.77–1.98)

1.28(0.73–2.23)

1.16(0.65–2.07)

13.1(8.46–20.3)

1.13(0.55–2.30)

1.82(1.40–2.35)

 Non-AIHA

1.43(0.84–2.43)

1.24(0.62–2.46)

1.28(0.65–2.50)

9.59(5.57–16.5)

1.23(0.53–2.88)

1.81(1.34–2.46)

 AIHA

0.91(0.41–2.01)

1.35(0.55–3.30)

0.95(0.35–2.61)

19.5(11.5–32.8)

0.98(0.34–2.85)

1.82(1.22–2.73)

  1. Model adjusted for age, sex, urbanization of residency, DM, SLE, alcohol-use disorders, splenomegaly, CKD, liver cirrhosis, HBV, HCV and RA
  2. Abbreviations: AHA acquired haemolytic anaemia, CKD chronic kidney disease, DM diabetes mellitus, HBV hepatitis B virus infection, HCV hepatitis C virus infection, RA rheumatoid arthritis, ref reference, SLE Systemic Lupus Erythematosus