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Table 3 Univariate and multivariate Cox analyses of max SUVmax versus standard prognostic factors for advanced RCC

From: FDG PET/CT as a prognostic biomarker in the era of molecular-targeting therapies: max SUVmax predicts survival of patients with advanced renal cell carcinoma

 

Univariate cox analyses

Multivariate cox analyses

Risk Fcotr

P value

HR

95 % CI

P value

HR

95 % CI

max SUVmax (continuous variable)

<0.001

1.257 

1.177-1.342

<0.001

1.265

1.159-1.380

Karnofsky performance status (<80 %)

0.036

2.107

1.051–4.221

0.296

0.623

0.256–1.514

Lactate dehydrogenase (>1.5x upper limit of normal)

<0.001

8.655

3.559–21.049

0.001

5.026

1.935–13.052

Corrected calcium (>10 mg/dl)

0.014

2.457

1.198–5.038

0.151

1.943

0.784–4.815

Hemoglobin (<lower limit of normal)

0.121

1.810

0.854–3.833

   

Interval from initial diagnosis to treatment (<1 year)

0.014

1.937

1.142–3.286

0.164

1.549

0.836–2.870

Age (>65 years old)

0.416

0.803

0.474–1.361

   

Sex (male or female)

0.890

1.046

0.551–1.984

   

Pathology (clear or non–clear)

0.044

2.113

1.021–4.373

0.962

0.980

0.419–2.291