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Table 3 Univariate and multivariate Cox analyses of max SUVmax versus standard prognostic factors for advanced RCC

From: FDG PET/CT as a prognostic biomarker in the era of molecular-targeting therapies: max SUVmax predicts survival of patients with advanced renal cell carcinoma

  Univariate cox analyses Multivariate cox analyses
Risk Fcotr P value HR 95 % CI P value HR 95 % CI
max SUVmax (continuous variable) <0.001 1.257  1.177-1.342 <0.001 1.265 1.159-1.380
Karnofsky performance status (<80 %) 0.036 2.107 1.051–4.221 0.296 0.623 0.256–1.514
Lactate dehydrogenase (>1.5x upper limit of normal) <0.001 8.655 3.559–21.049 0.001 5.026 1.935–13.052
Corrected calcium (>10 mg/dl) 0.014 2.457 1.198–5.038 0.151 1.943 0.784–4.815
Hemoglobin (<lower limit of normal) 0.121 1.810 0.854–3.833    
Interval from initial diagnosis to treatment (<1 year) 0.014 1.937 1.142–3.286 0.164 1.549 0.836–2.870
Age (>65 years old) 0.416 0.803 0.474–1.361    
Sex (male or female) 0.890 1.046 0.551–1.984    
Pathology (clear or non–clear) 0.044 2.113 1.021–4.373 0.962 0.980 0.419–2.291