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Fig. 5 | BMC Cancer

Fig. 5

From: Cooperation of Sox4 with β-catenin/p300 complex in transcriptional regulation of the Slug gene during divergent sarcomatous differentiation in uterine carcinosarcoma

Fig. 5

IHC findings in serial sections of UCS. a Staining by hematoxylin and eosin (HE) and by IHC for the indicated molecules. Note the predominant nuclear immunopositivity for Slug and β-catenin in sarcomatous components, but not carcinomatous lesions. Various combinations of nuclear immunopositivity for Sox4, Sox7, and Sox9 are also observed in both sarcomatous and carcinomatous components. Carcinomatous components are indicated by arrows. Sarcomatous components are magnified in the insets. Original magnification, x200 and x400 (insets). (Sa +/-), immunopositive or immunonegative in sarcomatous components; (Ca +/-), immunopositive or immunonegative in carcinomatous components. b IHC scores for the indicated molecules in carcinomatous (Ca) and sarcomatous (Sa) components of UCSs. The data shown are means ± SDs

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