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Table 5 Parameters of DCE-MRI according to pathologic biomarkers

From: US-localized diffuse optical tomography in breast cancer: comparison with pharmacokinetic parameters of DCE-MRI and with pathologic biomarkers

   Ktrans kep SER
(1/min) (1/min)
   Mean p Mean p Mean p
Overall        
Tumor size <2 cm (n = 20) 0.134 0.885 0.495 0.440 1.118 0.471
≥2 cm (n = 17) 0.131   0.468   1.085  
HG Low (n = 16) 0.136 0.829 0.484 0.965 1.136 0.199
High (n = 21) 0.131   0.481   1.077  
ER Neg (n = 15) 0.156 0.124 0.513 0.337 1.111 0.746
Pos (n = 22) 0.118   0.462   1.096  
PR Neg (n = 13) 0.154 0.162 0.485 0.932 1.119 0.613
Pos (n = 24) 0.122   0.481   1.091  
HER-2 Neg (n = 31) 0.138 0.051 0.487 0.684 1.109 0.526
Pos (n = 6) 0.107   0.458   1.069  
TNBC Neg (n = 27) 0.116 0.048 0.482 0.985 1.103 0.996
Pos (n = 10) 0.178   0.483   1.103  
Ki-67 Low (n = 18) 0.113 0.060 0.470 0.629 1.103 0.989
High (n = 19) 0.154   0.495   1.102  
LVI Neg (n = 23) 0.135 0.514 0.504 0.818 1.115 0.726
Pos (n = 3) 0.113   0.478   1.082  
LN mets Neg (n = 24) 0.123 0.206 0.498 0.412 1.112 0.581
Pos (n = 13) 0.152   0.453   1.085