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Fig. 3 | BMC Cancer

Fig. 3

From: Centrosome amplification induces high grade features and is prognostic of worse outcomes in breast cancer

Fig. 3

Centrosome amplification correlates with high ploidy and high CIN. a Centrosome number correlates with ploidy. b-e Breast tumors were divided into two groups based on the presence or absence of CA, which was defined as having an average of >2 centrosomes per cell, as in FigureĀ 2. Tumors with CA had higher average ploidy, as assessed by 6-chromosome FISH (b), polyploidy (c), and CIN, as assessed by the average non-modal chromosome number from FISH (e). d Centrosome number correlated with CIN. f Ploidy and CIN also correlated.

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