Skip to main content

Advertisement

Table 4 Comparative performance of CDRUG (existing method) and our models based on potency score, SVM and hybrid approach

From: Prediction of anticancer molecules using hybrid model developed on molecules screened against NCI-60 cancer cell lines

Method Sensitivity Specificity Accuracy MCC FPR AUC
CDRUG 65 - - - 0.05 0.88
74     0.10
81 - - - 0.20
Potency Score 65.8 98.9 83.5 0.7 0.02 0.95
74.26 98.42 87.15 0.76 0.02
84.62 96.45 90.94 0.82 0.05
SVM 65.47 98.66 83.34 0.69 0.02 0.95
74.16 97.63 86.8 0.75 0.03
89.02 91.52 90.42 0.81 0.09
Hybrid 65.57 99.63 83.75 0.71 0.01 0.98
74.41 99.11 87.59 0.77 0.01
92.38 92.55 92.47 0.85 0.08