Prediction of anticancer molecules using hybrid model developed on molecules screened against NCI-60 cancer cell lines

Table 3 Comparative performance of models developed using 126 fingerprints at various thresholds has been shown in this table

	SVM			Random Forest		IBK		Naïve Bayes
Threshold	Accuracy	MCC	Threshold	Accuracy	MCC	Accuracy	MCC	Accuracy	MCC
−1	72.40	0.54	0	46.63	0.00	46.63	0.00	46.63	0.00
−0.8	80.58	0.65	0.1	67.74	0.47	80.22	0.63	75.06	0.50
−0.6	84.72	0.72	0.2	77.73	0.61	82.59	0.67	74.99	0.50
−0.4	87.52	0.76	0.3	83.71	0.69	83.98	0.68	74.98	0.50
−0.2	89.60	0.79	0.4	86.33	0.73	85.71	0.72	74.92	0.50
0	90.40	0.81	0.5	87.47	0.75	85.31	0.71	74.86	0.49
0.2	90.24	0.80	0.6	86.47	0.73	85.10	0.71	74.79	0.49
0.4	89.00	0.79	0.7	83.81	0.69	82.73	0.67	74.79	0.49
0.6	86.35	0.74	0.8	79.03	0.62	81.22	0.65	74.81	0.49
0.8	82.65	0.68	0.9	71.86	0.51	80.90	0.65	74.77	0.49
1.0	70.49	0.48	1.0	59.30	0.28	80.87	0.65	73.37	0.48

ISSN: 1471-2407