Table 3 Incidence of AEs during PCT or PCRT according to CTCAE and Clavien-Dindo gradesa
CD0 group (n = 61) | CD1/2 group (n = 44) | CD3/4 group (n = 10) | Total (n = 115) | P Value | |
|---|---|---|---|---|---|
Anemia | 0.099 | ||||
Grade 0 | 6 (5.2) | 6 (5.2) | 0 (0.0) | 12 (10.4) | |
Grade 1/2 | 48 (41.7) | 27 (23.5) | 6 (5.2) | 81 (70.4) | |
Grade 3/4 | 7 (6.1) | 11 (9.6) | 4 (3.5) | 22 (19.1) | |
Leukopenia | 0.326 | ||||
Grade 0 | 24 (20.9) | 9 (7.8) | 4 (3.5) | 37 (32.2) | |
Grade 1/2 | 21 (18.3) | 21 (18.3) | 3 (2.6) | 45 (39.1) | |
Grade 3/4 | 16 (13.9) | 14 (12.2) | 3 (2.6) | 33 (28.7) | |
Neutropenia | 0.244 | ||||
Grade 0 | 16 (13.9) | 4 (3.5) | 3 (2.6) | 23 (20.0) | |
Grade 1/2 | 19 (16.5) | 16 (13.9) | 3 (2.6) | 38 (33.0) | |
Grade 3/4 | 26 (22.6) | 24 (20.9) | 4 (3.5) | 54 (47.0) | |
Febrile neutropenia | 0.829 | ||||
Grade 0 | 49 (42.6) | 35 (30.4) | 9 (7.8) | 93 (80.9) | |
Grade 3/4 | 12 (10.4) | 9 (7.8) | 1 (0.9) | 22 (19.1) | |
Lymphocytopenia | 0.748 | ||||
Grade 0 | 10 (8.7) | 9 (7.8) | 2 (1.7) | 21 (18.3) | |
Grade 1/2 | 41 (35.7) | 29 (25.2) | 5 (4.3) | 75 (65.2) | |
Grade 3/4 | 10 (8.7) | 6 (5.2) | 3 (2.6) | 19 (16.5) | |
Thrombocytopenia | 0.798 | ||||
Grade 0 | 39 (33.9) | 26 (22.6) | 8 (7.0) | 73 (63.5) | |
Grade 1/2 | 19 (16.5) | 16 (13.9) | 2 (1.7) | 37 (32.2) | |
Grade 3/4 | 3 (2.6) | 2 (1.7) | 0 (0.0) | 5 (4.3) | |
Increased ALT/AST | 0.718 | ||||
Grade 0 | 34 (29.6) | 28 (24.3) | 6 (5.2) | 68 (59.1) | |
Grade 1/2 | 27 (23.5) | 16 (13.9) | 4 (3.5) | 47 (40.9) | |
Increased Scr | 1.000 | ||||
Grade 0 | 58 (50.4) | 41 (35.7) | 9 (7.8) | 108 (93.9) | |
Grade 1/2 | 3 (2.6) | 3 (2.6) | 1 (0.9) | 7 (6.1) | |
Total AEs | 0.138 | ||||
Grade 0 | 0 (0.0) | 1 (0.9) | 0 (0.0) | 1 (0.9) | |
Grade 1/2 | 29 (25.2) | 11 (9.6) | 3 (2.6) | 43 (37.4) | |
Grade 3/4 | 32 (27.8) | 32 (27.8) | 7 (6.1) | 71 (61.7) | |