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Table 1 Characteristics of patients (n = 258)

From: Mutations in TP53 increase the risk of SOX2 copy number alterations and silencing of TP53 reduces SOX2 expression in non-small cell lung cancer

Age

 

(Mean ± SD)

63.9 ± 10.1

(Median, min-max)

66 (25–82)

Gender (male: female)

183/74

Smokers/Non-smokers

222/22

No cigarettes per day

 

(Mean ± SD)

15.3 ± 7.9

(Median, min-max)

14 (2–50)

Total years of smoking

 

(Mean ± SD)

41.3 ± 11.6

(Median, min-max)

43 (2–69)

Total pack-years*

 

(Mean ± SD)

31.6 ± 18.2

(Median, min-max)

28 (1–113)

Histology

 

Adenocarcinoma

118 (45.7 %)

Squamous cell carcinoma

103 (39.9 %)

Large cell carcinoma

36 (13.9 %)

Others

1

PAH-DNA adducts †

 

(Mean ± SD)

12.3 ± 8.9

(Median, min-max)

10 (1–46)

TP53 mutated/WT

134/101

  1. *Pack-years indicates the number of cigarettes smoked per day x number of years smoked/20. †PAH-DNA adducts per 108 nucleotides