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Table 1 Characteristics of patients (n = 258)

From: Mutations in TP53 increase the risk of SOX2 copy number alterations and silencing of TP53 reduces SOX2 expression in non-small cell lung cancer

Age  
(Mean ± SD) 63.9 ± 10.1
(Median, min-max) 66 (25–82)
Gender (male: female) 183/74
Smokers/Non-smokers 222/22
No cigarettes per day  
(Mean ± SD) 15.3 ± 7.9
(Median, min-max) 14 (2–50)
Total years of smoking  
(Mean ± SD) 41.3 ± 11.6
(Median, min-max) 43 (2–69)
Total pack-years*  
(Mean ± SD) 31.6 ± 18.2
(Median, min-max) 28 (1–113)
Histology  
Adenocarcinoma 118 (45.7 %)
Squamous cell carcinoma 103 (39.9 %)
Large cell carcinoma 36 (13.9 %)
Others 1
PAH-DNA adducts  
(Mean ± SD) 12.3 ± 8.9
(Median, min-max) 10 (1–46)
TP53 mutated/WT 134/101
  1. *Pack-years indicates the number of cigarettes smoked per day x number of years smoked/20. PAH-DNA adducts per 108 nucleotides
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