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Table 1 Summary of lesions seen in patient 1 after starting sorafenib treatment November 2007

From: (Secondary) solid tumors in thyroid cancer patients treated with the multi-kinase inhibitor sorafenib may present diagnostic challenges

Date

Lesion

February 2008

SCC on the back

Candida infection of the tongue

April 2008

Reactive epithelial skin lesion on the back without obvious atypia

Leukokeratosis of the tongue with atypia and inflammation

June 2008

Lesion with inverted follicular keratosis on the lower left leg

September 2009

Trichilemmoma of the nose

March 2010

Irritated verruca seborrhoica upper right leg

May 2010

Reactive epithelial hyperplasia of the tongue due to a candida infection

August 2011

Invasive squamous cell carcinoma of the tongue

Multiple lymph node metastasis of the SCC in the neck region

December 2011

SCC lymph node metastasis in the left axilla