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Table 1 IC50 of c-Met enzyme and cytotoxic assay

From: Novel c-Met inhibitor suppresses the growth of c-Met-addicted gastric cancer cells

 

IC50 (nM) in c-Met enzyme assay

IC50 (nM) in Hs746T cell cytotoxic assay

KRC-00509

6.3

3.4

KRC-00715

9.0

39

Crizotinib

2.2

10.0