Table 2 Trabectedin-related toxicities
Type of toxicity | Grade 1 n (%) | Grade 2 n (%) | Grade 3 n (%) | Grade 4 n (%) | Grade 5 n (%) |
|---|---|---|---|---|---|
Hematological | |||||
 Anemia | 8 (10.4) | 3 (3.9) | 6 (7.8) | - | - |
 Low ANC | 1 (1.3) | 24 (32.4) | 15 (20.3) | 4 (5.2) | - |
 Thrombocytopenia | 5 (6.5) | - | 1 (1.3) | 2 (2.6) | - |
 Lymphoenia | 1 (1.3) | - | 1 (1.3) | - | - |
 Febrile neutropenia | - | - | 2 (2.6) | - | - |
Biochemical | |||||
 Elevated ALP | 12 (15.6) | 2 (2.6) | 4 (5.2) | 2 (2.6) | - |
 Elevated GGT | 10 (12.9) | 2 (2.6) | 5 (6.5) | 2 (2.6) | - |
 Elevated CK | 4 (5.2) | 1 (1.3) | 1 (1.3) | 2 (2.6) | 2 (2.6) |
 Elevated AST | 3 (3.9) | 2 (2.6) | 5 (6.5) | 2 (2.6) | - |
 Elevated ALT | 6 (7.8) | 1 (1.3) | 5 (6.5) | 3 (3.9) | - |
 Elevated bilirubin | - | - | 1 (1.3) | - | - |