Skip to main content

Advertisement

Springer Nature is making SARS-CoV-2 and COVID-19 research free. View research | View latest news | Sign up for updates

Table 2 Trabectedin-related toxicities

From: Trabectedin for inoperable or recurrent soft tissue sarcoma in adult patients: a retrospective cohort study

Type of toxicity Grade 1 n (%) Grade 2 n (%) Grade 3 n (%) Grade 4 n (%) Grade 5 n (%)
Hematological
 Anemia 8 (10.4) 3 (3.9) 6 (7.8) - -
 Low ANC 1 (1.3) 24 (32.4) 15 (20.3) 4 (5.2) -
 Thrombocytopenia 5 (6.5) - 1 (1.3) 2 (2.6) -
 Lymphoenia 1 (1.3) - 1 (1.3) - -
 Febrile neutropenia - - 2 (2.6) - -
Biochemical
 Elevated ALP 12 (15.6) 2 (2.6) 4 (5.2) 2 (2.6) -
 Elevated GGT 10 (12.9) 2 (2.6) 5 (6.5) 2 (2.6) -
 Elevated CK 4 (5.2) 1 (1.3) 1 (1.3) 2 (2.6) 2 (2.6)
 Elevated AST 3 (3.9) 2 (2.6) 5 (6.5) 2 (2.6) -
 Elevated ALT 6 (7.8) 1 (1.3) 5 (6.5) 3 (3.9) -
 Elevated bilirubin - - 1 (1.3) - -
  1. ALP alkaline phosphatase, ALT alanine transaminase, ANC absolute neutrophil count, AST aspartate aminotransferase, CK creatine kinase, GGT gamma-glutamyl transferase