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Table 4 Clinical and pathologic characteristics of the study cases according to the heterogeneity of mutation

From: Genetic heterogeneity of actionable genes between primary and metastatic tumor in lung adenocarcinoma

  

Homogenous (n = 28)

Heterogeneous (n = 13)

P-value

Age (mean ± SD); yrs

 

59.7 ± 12.31

59.6 ± 8.17

0.996*

Gender

Male

9

4

0.930**

 

Female

19

9

 

Smoking status

Never smoker

22

11

0.132**

 

Current smoker

1

2

 
 

Ex-smoker

5

0

 

pStage

IIA

12

5

0.331**

 

IIB

0

1

 
 

IIIA

16

7

 

Maximum tumor diameter (cm)

 

3.0 ± 1.02

3.28 ± 1.15

0.401*

Histologic subtype

Lepidic predominant

0

1

 
 

Acinar predominant

20

9

0.732**

 

Papillary and micropapillary predominant

6

2

 
 

Othersa

2

1

 
  1. *P-value was obtained from t-test; **P-value was obtained from Pearson’s Chi-square test; aincludes solid types and invasive mucinous adenocarcinoma