Skip to main content

Advertisement

Table 4 Clinical and pathologic characteristics of the study cases according to the heterogeneity of mutation

From: Genetic heterogeneity of actionable genes between primary and metastatic tumor in lung adenocarcinoma

   Homogenous (n = 28) Heterogeneous (n = 13) P-value
Age (mean ± SD); yrs   59.7 ± 12.31 59.6 ± 8.17 0.996*
Gender Male 9 4 0.930**
  Female 19 9  
Smoking status Never smoker 22 11 0.132**
  Current smoker 1 2  
  Ex-smoker 5 0  
pStage IIA 12 5 0.331**
  IIB 0 1  
  IIIA 16 7  
Maximum tumor diameter (cm)   3.0 ± 1.02 3.28 ± 1.15 0.401*
Histologic subtype Lepidic predominant 0 1  
  Acinar predominant 20 9 0.732**
  Papillary and micropapillary predominant 6 2  
  Othersa 2 1  
  1. *P-value was obtained from t-test; **P-value was obtained from Pearson’s Chi-square test; aincludes solid types and invasive mucinous adenocarcinoma