Skip to main content

Table 2 Sensitivity of native leukemia blasts in response to THC

From: Dronabinol has preferential antileukemic activity in acute lymphoblastic and myeloid leukemia with lymphoid differentiation patterns

Patient No. Phenotype    THC response
Entity lineage dependency is marked (+) aberrantly expressed antigens are separately indicated % viable cells at 50 μM
  T-lymphatic B-lymphatic myeloid  
AML-1     
sAML (MDS) N/A N/A + 100
AML-2     
AML, FLT3-ITD + 100
AML-3     
AML NOS (CD3) + 100
AML−4     
APL + 99
AML-5     
AML, FLT3-ITD + 96
AML-6     
AML, FLT3-ITD CD19 + 91
AML-7     
AML NOS (M0) + 89
AML-8     
AML, FLT3-ITD + 88
AML-9     
N/A N/A N/A + 69
AML-10 CD7    
AML, FLT3-ITD CD56 + 50
AML-11 CD7    
sAML (MDS) CD5 + 46
AML-12 (CD7)    
AML NOS (M0) (CD5) + 33
AML-13 CD7    
CBF AML CD5 + 20
ALL-1     
(c) B-ALL + 97
ALL-2    CD33  
pre B-ALL + CD13 96
ALL-3     
(c) B-ALL + CD33 94
ALL-4     
pre-B-ALL + 82
ALL-5     
(c) B-ALL + 55
ALL-6     
Cortical T-ALL + CD79 55
ALL-7     
(c) B-ALL + 54
ALL-8   + CD33  
pre B-ALL CD10 CD13 53
ALL-9     
(c) B-ALL + 48
ALL-10     
(c) B-ALL + 43
ALL-11     
Cortical T-ALL + 38
ALL-12    CD33  
(c) B-ALL + CD13 37
ALL-13 CD56    
pre B-ALL CD1a + CD13 12