TY - JOUR AU - Matsuda, L. A. AU - Lolait, S. J. AU - Brownstein, M. J. AU - Young, A. C. AU - Bonner, T. I. PY - 1990 DA - 1990// TI - Structure of a cannabinoid receptor and functional expression of the cloned cDNA JO - Nature VL - 346 UR - https://doi.org/10.1038/346561a0 DO - 10.1038/346561a0 ID - Matsuda1990 ER - TY - JOUR AU - Munro, S. AU - Thomas, K. L. AU - Abu-Shaar, M. PY - 1993 DA - 1993// TI - Molecular characterization of a peripheral receptor for cannabinoids JO - Nature VL - 365 UR - https://doi.org/10.1038/365061a0 DO - 10.1038/365061a0 ID - Munro1993 ER - TY - JOUR AU - Galve-Roperh, I. AU - Sanchez, C. AU - Cortes, M. L. AU - Gomez del Pulgar, T. AU - Izquierdo, M. AU - Guzman, M. PY - 2000 DA - 2000// TI - Anti-tumoral action of cannabinoids: involvement of sustained ceramide accumulation and extracellular signal-regulated kinase activation JO - Nat Med VL - 6 UR - https://doi.org/10.1038/73171 DO - 10.1038/73171 ID - Galve-Roperh2000 ER - TY - JOUR AU - Golech, S. A. AU - McCarron, R. M. AU - Chen, Y. AU - Bembry, J. AU - Lenz, F. AU - Mechoulam, R. PY - 2004 DA - 2004// TI - Human brain endothelium: coexpression and function of vanilloid and endocannabinoid receptors JO - Brain Res Mol Brain Res VL - 132 UR - https://doi.org/10.1016/j.molbrainres.2004.08.025 DO - 10.1016/j.molbrainres.2004.08.025 ID - Golech2004 ER - TY - JOUR AU - Ofek, O. AU - Karsak, M. AU - Leclerc, N. AU - Fogel, M. AU - Frenkel, B. AU - Wright, K. PY - 2006 DA - 2006// TI - Peripheral cannabinoid receptor, CB2, regulates bone mass JO - Proc Natl Acad Sci U S A VL - 103 UR - https://doi.org/10.1073/pnas.0504187103 DO - 10.1073/pnas.0504187103 ID - Ofek2006 ER - TY - JOUR AU - Casanova, M. L. AU - Blazquez, C. AU - Martinez-Palacio, J. AU - Villanueva, C. AU - Fernandez-Acenero, M. J. AU - Huffman, J. W. PY - 2003 DA - 2003// TI - Inhibition of skin tumor growth and angiogenesis in vivo by activation of cannabinoid receptors JO - J Clin Invest VL - 111 UR - https://doi.org/10.1172/JCI200316116 DO - 10.1172/JCI200316116 ID - Casanova2003 ER - TY - JOUR AU - Basu, S. AU - Dittel, B. N. PY - 2011 DA - 2011// TI - Unraveling the complexities of cannabinoid receptor 2 (CB2) immune regulation in health and disease JO - Immunol Res VL - 51 UR - https://doi.org/10.1007/s12026-011-8210-5 DO - 10.1007/s12026-011-8210-5 ID - Basu2011 ER - TY - JOUR AU - Pertwee, R. G. PY - 2012 DA - 2012// TI - Targeting the endocannabinoid system with cannabinoid receptor agonists: pharmacological strategies and therapeutic possibilities JO - Philos Trans R Soc Lond B Biol Sci VL - 367 UR - https://doi.org/10.1098/rstb.2011.0381 DO - 10.1098/rstb.2011.0381 ID - Pertwee2012 ER - TY - JOUR AU - Guzman, M. PY - 2003 DA - 2003// TI - Cannabinoids: potential anticancer agents JO - Nat Rev Cancer VL - 3 UR - https://doi.org/10.1038/nrc1188 DO - 10.1038/nrc1188 ID - Guzman2003 ER - TY - JOUR AU - Lombard, C. AU - Nagarkatti, M. AU - Nagarkatti, P. S. PY - 2005 DA - 2005// TI - Targeting cannabinoid receptors to treat leukemia: role of cross-talk between extrinsic and intrinsic pathways in Delta9-tetrahydrocannabinol (THC)-induced apoptosis of Jurkat cells JO - Leuk Res VL - 29 UR - https://doi.org/10.1016/j.leukres.2005.01.014 DO - 10.1016/j.leukres.2005.01.014 ID - Lombard2005 ER - TY - JOUR AU - Herrera, B. AU - Carracedo, A. AU - Diez-Zaera, M. AU - Guzman, M. AU - Velasco, G. PY - 2005 DA - 2005// TI - p38 MAPK is involved in CB2 receptor-induced apoptosis of human leukaemia cells JO - FEBS Lett VL - 579 UR - https://doi.org/10.1016/j.febslet.2005.08.021 DO - 10.1016/j.febslet.2005.08.021 ID - Herrera2005 ER - TY - JOUR AU - Sancho, R. AU - Vega, L. AU - Appendino, G. AU - Marzo, V. AU - Macho, A. AU - Munoz, E. PY - 2003 DA - 2003// TI - The CB1/VR1 agonist arvanil induces apoptosis through an FADD/caspase-8-dependent pathway JO - Br J Pharmacol VL - 140 UR - https://doi.org/10.1038/sj.bjp.0705532 DO - 10.1038/sj.bjp.0705532 ID - Sancho2003 ER - TY - JOUR AU - Alberich Jorda, M. AU - Rayman, N. AU - Tas, M. AU - Verbakel, S. E. AU - Battista, N. AU - Lom, K. PY - 2004 DA - 2004// TI - The peripheral cannabinoid receptor Cb2, frequently expressed on AML blasts, either induces a neutrophilic differentiation block or confers abnormal migration properties in a ligand-dependent manner JO - Blood VL - 104 UR - https://doi.org/10.1182/blood-2003-12-4357 DO - 10.1182/blood-2003-12-4357 ID - Alberich Jorda2004 ER - TY - JOUR AU - Valk, P. J. AU - Delwel, R. PY - 1998 DA - 1998// TI - The peripheral cannabinoid receptor, Cb2, in retrovirally-induced leukemic transformation and normal hematopoiesis JO - Leuk Lymphoma VL - 32 UR - https://doi.org/10.3109/10428199809059244 DO - 10.3109/10428199809059244 ID - Valk1998 ER - TY - JOUR AU - Valk, P. AU - Verbakel, S. AU - Vankan, Y. AU - Hol, S. AU - Mancham, S. AU - Ploemacher, R. PY - 1997 DA - 1997// TI - Anandamide, a natural ligand for the peripheral cannabinoid receptor is a novel synergistic growth factor for hematopoietic cells JO - Blood VL - 90 ID - Valk1997 ER - TY - JOUR AU - Carracedo, A. AU - Lorente, M. AU - Egia, A. AU - Blazquez, C. AU - Garcia, S. AU - Giroux, V. PY - 2006 DA - 2006// TI - The stress-regulated protein p8 mediates cannabinoid-induced apoptosis of tumor cells JO - Cancer Cell VL - 9 UR - https://doi.org/10.1016/j.ccr.2006.03.005 DO - 10.1016/j.ccr.2006.03.005 ID - Carracedo2006 ER - TY - JOUR AU - Kampa-Schittenhelm, K. M. AU - Heinrich, M. C. AU - Akmut, F. AU - Rasp, K. H. AU - Illing, B. AU - Dohner, H. PY - 2013 DA - 2013// TI - Cell cycle-dependent activity of the novel dual PI3K-MTORC1/2 inhibitor NVP-BGT226 in acute leukemia JO - Mol Cancer VL - 12 UR - https://doi.org/10.1186/1476-4598-12-46 DO - 10.1186/1476-4598-12-46 ID - Kampa-Schittenhelm2013 ER - TY - JOUR AU - Kampa-Schittenhelm, K. M. AU - Heinrich, M. C. AU - Akmut, F. AU - Dohner, H. AU - Dohner, K. AU - Schittenhelm, M. M. PY - 2013 DA - 2013// TI - Quizartinib (AC220) is a potent second generation class III tyrosine kinase inhibitor that displays a distinct inhibition profile against mutant-FLT3, -PDGFRA and -KIT isoforms JO - Mol Cancer VL - 12 UR - https://doi.org/10.1186/1476-4598-12-19 DO - 10.1186/1476-4598-12-19 ID - Kampa-Schittenhelm2013 ER - TY - JOUR AU - Matsuo, Y. AU - MacLeod, R. A. AU - Uphoff, C. C. AU - Drexler, H. G. AU - Nishizaki, C. AU - Katayama, Y. PY - 1997 DA - 1997// TI - Two acute monocytic leukemia (AML-M5a) cell lines (MOLM-13 and MOLM-14) with interclonal phenotypic heterogeneity showing MLL-AF9 fusion resulting from an occult chromosome insertion, ins(11;9)(q23;p22p23) JO - Leukemia VL - 11 UR - https://doi.org/10.1038/sj.leu.2400768 DO - 10.1038/sj.leu.2400768 ID - Matsuo1997 ER - TY - JOUR AU - Jorda, M. A. AU - Rayman, N. AU - Valk, P. AU - Wee, E. AU - Delwel, R. PY - 2003 DA - 2003// TI - Identification, characterization, and function of a novel oncogene: the peripheral cannabinoid receptor Cb2 JO - Ann N Y Acad Sci VL - 996 UR - https://doi.org/10.1111/j.1749-6632.2003.tb03227.x DO - 10.1111/j.1749-6632.2003.tb03227.x ID - Jorda2003 ER - TY - JOUR AU - Herkenham, M. AU - Lynn, A. B. AU - Little, M. D. AU - Johnson, M. R. AU - Melvin, L. S. AU - Costa, B. R. PY - 1990 DA - 1990// TI - Cannabinoid receptor localization in brain JO - Proc Natl Acad Sci U S A VL - 87 UR - https://doi.org/10.1073/pnas.87.5.1932 DO - 10.1073/pnas.87.5.1932 ID - Herkenham1990 ER - TY - JOUR AU - McKallip, R. J. AU - Lombard, C. AU - Fisher, M. AU - Martin, B. R. AU - Ryu, S. AU - Grant, S. PY - 2002 DA - 2002// TI - Targeting CB2 cannabinoid receptors as a novel therapy to treat malignant lymphoblastic disease JO - Blood VL - 100 UR - https://doi.org/10.1182/blood-2002-01-0098 DO - 10.1182/blood-2002-01-0098 ID - McKallip2002 ER - TY - JOUR AU - Powles, T. AU - Poele, R. AU - Shamash, J. AU - Chaplin, T. AU - Propper, D. AU - Joel, S. PY - 2005 DA - 2005// TI - Cannabis-induced cytotoxicity in leukemic cell lines: the role of the cannabinoid receptors and the MAPK pathway JO - Blood VL - 105 UR - https://doi.org/10.1182/blood-2004-03-1182 DO - 10.1182/blood-2004-03-1182 ID - Powles2005 ER - TY - JOUR AU - Koch, S. AU - Mayer, F. AU - Honecker, F. AU - Schittenhelm, M. AU - Bokemeyer, C. PY - 2003 DA - 2003// TI - Efficacy of cytotoxic agents used in the treatment of testicular germ cell tumours under normoxic and hypoxic conditions in vitro JO - Br J Cancer VL - 89 UR - https://doi.org/10.1038/sj.bjc.6601375 DO - 10.1038/sj.bjc.6601375 ID - Koch2003 ER - TY - JOUR AU - Singh, Y. AU - Bali, C. PY - 2013 DA - 2013// TI - Cannabis extract treatment for terminal acute lymphoblastic leukemia with a Philadelphia chromosome mutation JO - Case Rep Oncol VL - 6 UR - https://doi.org/10.1159/000356446 DO - 10.1159/000356446 ID - Singh2013 ER - TY - JOUR AU - Yokota, S. AU - Kiyoi, H. AU - Nakao, M. AU - Iwai, T. AU - Misawa, S. AU - Okuda, T. PY - 1997 DA - 1997// TI - Internal tandem duplication of the FLT3 gene is preferentially seen in acute myeloid leukemia and myelodysplastic syndrome among various hematological malignancies. A study on a large series of patients and cell lines JO - Leukemia VL - 11 UR - https://doi.org/10.1038/sj.leu.2400812 DO - 10.1038/sj.leu.2400812 ID - Yokota1997 ER - TY - JOUR AU - Beghini, A. AU - Magnani, I. AU - Ripamonti, C. B. AU - Larizza, L. PY - 2002 DA - 2002// TI - Amplification of a novel c-Kit activating mutation Asn(822)-Lys in the Kasumi-1 cell line: a t(8;21)-Kit mutant model for acute myeloid leukemia JO - Hematol J VL - 3 UR - https://doi.org/10.1038/sj.thj.6200168 DO - 10.1038/sj.thj.6200168 ID - Beghini2002 ER - TY - JOUR AU - Schittenhelm, M. M. AU - Shiraga, S. AU - Schroeder, A. AU - Corbin, A. S. AU - Griffith, D. AU - Lee, F. Y. PY - 2006 DA - 2006// TI - Dasatinib (BMS-354825), a dual SRC/ABL kinase inhibitor, inhibits the kinase activity of wild-type, juxtamembrane, and activation loop mutant KIT isoforms associated with human malignancies JO - Cancer Res VL - 66 UR - https://doi.org/10.1158/0008-5472.CAN-05-2050 DO - 10.1158/0008-5472.CAN-05-2050 ID - Schittenhelm2006 ER -