Skip to main content

Advertisement

Fig. 6 | BMC Cancer

Fig. 6

From: Role of HLA-G and extracellular vesicles in renal cancer stem cell-induced inhibition of dendritic cell differentiation

Fig. 6

The use of specific blocking antibody against HLA-G partially reverted the inhibitory effect on monocyte-derived DC differentiation induced by CD105+ CSC EVs. a Mean percentages ± SD of CD14 expression by monocyte-derived DCs stimulated with CD105+ EVs in the presence or in absence (CD105+ EV Mo) of specific blocking antibody against HLA-G (CD105+ EV Mo + anti HLA-G). Results were obtained from 2 independent experiments. T Student test was performed: *p < 0.05 CD105+ EV Mo versus CD105+ EV Mo + anti HLA-G. b MFI ± SD of CD80, CD86, ΗLA-DR, CD1a and α5 integrin of monocyte-derived DCs stimulated with CD105+ EVs in the presence or in absence (CD105+ EV Mo) of specific blocking antibody against HLA-G (CD105+ EV Mo + anti HLA-G). T Student test was performed: *p < 0.05 CD105+ EV Mo versus CD105+ EV Mo + anti HLA-G

Back to article page