Fig. 1

RT-PCR analysis of RIZ1 mRNA expression in different grade of gliomas as well as in U87 and U251 GBM cell lines (a). II: LGG, III and IV: HGG. Human breast cancer MCF-7 cells served as a positive control. PFS (b) and OS (c) associated with RIZ1 immunoreactivity in patients with gliomas. Three independent experiments were performed. *P < 0.05 as compared with control groups