Variables | Categories | Early stage | Advanced stage | ||||
---|---|---|---|---|---|---|---|
HR | 95 % CI | P valueb | HR | 95 % CI | P valueb | ||
Age (years) | ≥60/<60 | 1.705 | 0.860-3.381 | 0.127 | 2.229 | 1.264-3.932 | 0.006 |
Sex | Male/female | 0.818 | 0.462-1.447 | 0.489 | 1.575 | 0.934-2.658 | 0.089 |
Tumor location | Colon/rectum | 1.095 | 0.802-1.495 | 0.569 | 0.968 | 0.727-1.290 | 0.826 |
Tumor size (cm) | ≥5/<5 | 0.920 | 0.536-1.579 | 0.762 | 1.558 | 0.915-2.652 | 0.103 |
No. of examined lymph nodes | ≥12/< 12 | 1.525 | 0.785-2.964 | 0.213 | 0.584 | 0.351-0.973 | 0.039 |
Bowel obstruction/perforation | Yes/no | 1.365 | 0.175-10.672 | 0.767 | 0.689 | 0.209-2.269 | 0.541 |
Adjuvant chemotherapya | Yes/no | 0.808 | 0.397-1.644 | 0.556 | |||
Differentiation grade | Poor/well + moderate | 0.690 | 0.207-2.298 | 0.545 | 1.591 | 0.946-2.678 | 0.080 |
NETO2 expression | High/low | 1.937 | 1.107-3.390 | 0.021 | 2.241 | 1.245-4.035 | 0.007 |