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Table 3 Univariate and multivariate analyses of prognostic factors for disease-specific survival of CRC patients in the study cohort

From: Upregulation of NETO2 expression correlates with tumor progression and poor prognosis in colorectal carcinoma

Variables Categories Univariate analysis Multivariate analysis
   HR 95 % CI P valuea HR 95 % CI P valuea
Age (years) ≥60/<60 1.674 1.098-2.551 0.017 1.875 1.225-2.871 0.004
Sex Male/female 1.141 0.791-1.646 0.480    
Tumor location Colon/rectum 0.960 0.674-1.367 0.820    
Tumor size (cm) ≥5/<5 1.161 0.807-1.672 0.421    
No. of examined lymph nodes ≥12/< 12 0.952 0.669-1.354 0.783    
Bowel obstruction/perforation Yes/no 0.962 0.355-2.607 0.940    
Adjuvant chemotherapy Yes/no 1.246 0.851-1.825 0.259    
Differentiation grade Poor well + moderate 1.691 1.103-2.591 0.016    
TNM stage III/I+ II 1.832 1.286-2.609 0.001 1.878 1.313-2.685 0.001
NETO2 expression High/low 1.986 1.343-2.937 0.001 1.924 1.300-2.848 0.001
  1. Abbreviations: HR, hazard ratio; 95 % CI, 95 % confidence interval
  2. aBold type indicates statistical significance