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Table 2 Association between NETO2 expression and clinicopathologic characteristics of CRC patients in the study cohort

From: Upregulation of NETO2 expression correlates with tumor progression and poor prognosis in colorectal carcinoma

Characteristics No. of patients (%) NETO2 expression  
Low (%) High (%) P value a
(n = 292) (n = 115) (n = 177)
Age (years)     0.864
  <60 88 (30.1) 34 (29.6) 54 (30.5)  
  ≥60 204 (69.9) 81 (70.4) 123 (69.5)  
Sex     0.860
  Female 111 (38.0) 43 (37.4) 68 (38.4)  
  Male 181 (62.0) 72 (62.6) 109 (61.6)  
Tumor location     0.227
  Right colon 88 (30.1) 31 (27.0) 37 (20.9)  
  Left colon 71 (24.4) 34 (29.5) 57 (32.2)  
  Rectum 133 (45.5) 50 (43.5) 83 (46.9)  
Differentiation grade    0.013
  Well 20 (6.8) 12 (10.4) 8 (4.5)  
  Moderate 222 (76.0) 91 (79.2) 131 (74.0)  
  Poor 50 (17.2) 12 (10.4) 38 (21.5)  
Tumor size (cm)     0.446
  <5 114 (39.0) 48 (41.7) 66 (37.3)  
  ≥5 178 (61.0) 67 (58.3) 111 (62.7)  
Local invasion     0.049
  T1-T2 48 (16.4) 25 (21.7) 23 (13.0)  
  T3-T4 244 (83.6) 90 (78.3) 154 (87.0)  
Lymph node metastasis    0.009
  N0 164 (56.2) 74 (64.3) 90 (50.8)  
  N1 101 (34.6) 37 (32.2) 64 (36.2)  
  N2 27 (9.2) 4 (3.5) 23 (13.0)  
TNM stage     0.041
  I 40 (13.7) 21 (18.3) 19 (10.7)  
  II 124 (42.5) 53 (46.1) 71 (40.1)  
  III 128 (43.8) 41 (35.6) 87 (49.2)  
No. of examined lymph nodes    0.655
  <12 152 (52.1) 58 (50.4) 94 (53.1)  
  ≥12 140 (47.9) 57 (49.6) 83 (46.9)  
Bowel obstruction/perforation    0.537
  No 282 (96.6) 112 (97.4) 170 (96.0)  
  Yes 10 (3.4) 3 (2.6) 7 (4.0)  
Adjuvant chemotherapy    0.060
  No 98 (33.6) 46 (40.0) 52 (29.4)  
  Yes 194 (66.4) 69 (60.0) 125 (70.6)  
Death     0.001
  No 168 (57.5) 80 (69.6) 88 (49.7)  
  Yes 124 (42.5) 35 (30.4) 89 (50.3)  
  1. aPearson chi-square test or Fisher exact test was used for comparison between subgroups. Bold type indicates statistical significance