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Table 1 Patient characteristics

From: Alpha-fetoprotein normalization as a prognostic surrogate in small hepatocellular carcinoma after stereotactic body radiotherapy: a propensity score matching analysis

Variables All patients (n = 77) Propensity score matched patients (50 pairs)
Normalized group Non-normalized group P Normalized group Non-normalized group p
(n = 37) (n = 40) (n = 25) (n = 25)
No. of patients (%) No. of patients (%) No. of patients (%) No. of patients (%)
Age (years)    0.279    0.929
Median 62 59   58 60  
Range 47–78 39–78   50–69 39–78  
Gender    0.550    0.747
Male 29 (78.4) 29 (72.5)   19 (76.0) 18 (72.0)  
Female 8 (21.6) 11 (27.5)   6 (24.0) 7 (28.0)  
ECOG PS    0.197    0.156
0 23 (62.2) 19 (47.5)   16 (64.0) 11 (44.0)  
1–2 14 (37.8) 21 (52.5)   9 (36.0) 14 (56.0)  
Child-Pugh classification    0.945    0.480
A 28 (75.7) 30 (75.0)   19 (76.0) 21 (84.0)  
B 9 (24.3) 10 (25.0)   6 (24.0) 4 (16.0)  
Viral etiology    0.402    1.000
HBs-Ag (+) 29 (78.4) 28 (70.0)   20 (80.0) 20 (80.0)  
HBs-Ag (−) 8 (21.6) 12 (30.0)   5 (20.0) 5 (20.0)  
Tumor size (cm)    0.488    0.344
Median 2.0 1.7   2.1 1.6  
Range 0.8–4.5 1.0–4.4   1.0–4.5 1.2–3.6  
Initial AFP (ng/mL)    0.187    0.655
Median 48.6 128.0   50.2 113.0  
Range 20.8–1870.0 20.3–3250.0   21.2–1870.0 20.3–2490.0  
ALT    0.093    0.981
Median 25 28.5   27 25  
Range 9–55 11–185   9–55 14–116  
Albumin    0.383    0.395
Median 3.6 3.4   3.4 3.6  
Range 2.4–4.5 2.4–4.7   2.4–4.5 2.9–4.7  
Bilirubin    0.841    0.804
Median 1.1 1.1   1.0 1.0  
Range 0.5–3.5 0.6–6.2   0.5–2.9 0.6–6.2  
INR    0.550    0.514
Median 1.1 1.1   1.2 1.1  
Range 0.9–1.5 0.9–1.7   0.9–1.5 0.9–1.7  
Radiation dose    0.909    0.743
Median 45 45   45 45  
Range 36–60 36–60   36–60 36–60  
  1. Abbreviations: ECOG PS Eastern Cooperative Oncology Group performance status, HBs-Ag hepatitis B surface-antigen, AFP alpha-fetoprotein, ALT alanine aminotransferase, INR international normalized ratio