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Table 1 Patient characteristics

From: Alpha-fetoprotein normalization as a prognostic surrogate in small hepatocellular carcinoma after stereotactic body radiotherapy: a propensity score matching analysis

Variables

All patients (n = 77)

Propensity score matched patients (50 pairs)

Normalized group

Non-normalized group

P

Normalized group

Non-normalized group

p

(n = 37)

(n = 40)

(n = 25)

(n = 25)

No. of patients (%)

No. of patients (%)

No. of patients (%)

No. of patients (%)

Age (years)

  

0.279

  

0.929

Median

62

59

 

58

60

 

Range

47–78

39–78

 

50–69

39–78

 

Gender

  

0.550

  

0.747

Male

29 (78.4)

29 (72.5)

 

19 (76.0)

18 (72.0)

 

Female

8 (21.6)

11 (27.5)

 

6 (24.0)

7 (28.0)

 

ECOG PS

  

0.197

  

0.156

0

23 (62.2)

19 (47.5)

 

16 (64.0)

11 (44.0)

 

1–2

14 (37.8)

21 (52.5)

 

9 (36.0)

14 (56.0)

 

Child-Pugh classification

  

0.945

  

0.480

A

28 (75.7)

30 (75.0)

 

19 (76.0)

21 (84.0)

 

B

9 (24.3)

10 (25.0)

 

6 (24.0)

4 (16.0)

 

Viral etiology

  

0.402

  

1.000

HBs-Ag (+)

29 (78.4)

28 (70.0)

 

20 (80.0)

20 (80.0)

 

HBs-Ag (−)

8 (21.6)

12 (30.0)

 

5 (20.0)

5 (20.0)

 

Tumor size (cm)

  

0.488

  

0.344

Median

2.0

1.7

 

2.1

1.6

 

Range

0.8–4.5

1.0–4.4

 

1.0–4.5

1.2–3.6

 

Initial AFP (ng/mL)

  

0.187

  

0.655

Median

48.6

128.0

 

50.2

113.0

 

Range

20.8–1870.0

20.3–3250.0

 

21.2–1870.0

20.3–2490.0

 

ALT

  

0.093

  

0.981

Median

25

28.5

 

27

25

 

Range

9–55

11–185

 

9–55

14–116

 

Albumin

  

0.383

  

0.395

Median

3.6

3.4

 

3.4

3.6

 

Range

2.4–4.5

2.4–4.7

 

2.4–4.5

2.9–4.7

 

Bilirubin

  

0.841

  

0.804

Median

1.1

1.1

 

1.0

1.0

 

Range

0.5–3.5

0.6–6.2

 

0.5–2.9

0.6–6.2

 

INR

  

0.550

  

0.514

Median

1.1

1.1

 

1.2

1.1

 

Range

0.9–1.5

0.9–1.7

 

0.9–1.5

0.9–1.7

 

Radiation dose

  

0.909

  

0.743

Median

45

45

 

45

45

 

Range

36–60

36–60

 

36–60

36–60

 
  1. Abbreviations: ECOG PS Eastern Cooperative Oncology Group performance status, HBs-Ag hepatitis B surface-antigen, AFP alpha-fetoprotein, ALT alanine aminotransferase, INR international normalized ratio