Skip to main content
Fig. 6 | BMC Cancer

Fig. 6

From: All-trans retinoic acid synergizes with topotecan to suppress AML cells via promoting RARα-mediated DNA damage

Fig. 6

Efficacy of TPT combined with ATRA treatment regimen in vivo. Mice transplanted with HL60 human xenografts were randomly divided into 4 groups and given injection of TPT (2 mg/kg, i.p.), ATRA (5 mg/kg, i.g.), combination, or vehicle for a period of 9 days. a Relative tumor volume was expressed as mean ± SD (n = 3 per group). b The average body weight of each group was expressed as mean ± SD (n = 3 per group). c Representative fluorescence images of TUNEL staining of tumor tissues collected from each group (magnification 100x)

Back to article page