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Table 6 Univariable and multivariable Cox proportional analyses of clinico-pathological parameters with regard to disease free survival

From: Neutrophil/Lymphocyte ratio has no predictive or prognostic value in breast cancer patients undergoing preoperative systemic therapy

Parameter Univariable analyses Multivariable analyses
  No recurrence Recurrence HR (95 % CI) p value HR (95 % CI) p value
Tumor grade     0.041   0.353
 G1 + G2 69 32 1.00 1.00
 G3 70 52 1.534 (1.017-2.314) 1.278 (0.762-2.142)
PR (biopsy)     0.034   0.002
 Negative 58 46 1.00 1.00
 Positive 91 43 0.655 (0.443-0.968) 0.448 (0.268-0.748)
cT pretreatment     0.001   0.002
 cT1 + cT2 100 37 1.00 1.00
 cT3 + cT4 44 49 1.955 (1.309-2.919) 2.244 (1.342-3.750)
pN (tumor)       
 pN0 72 19 1.00   1.00  
 pN1 60 52 3.255 (1.929-5.492) <0.001 2.813 (1.440-5.496) <0.002
 pN2 + pN3 15 18 4.003 (2.057-7.788) <0.001 6.793 (3.070-15.030) <0.001
NLR 150 95 0.978 (0.932-1.026) 0.363 1.009 (0.957-1.064) 0.738
  1. Abbreviations: CI confidence interval, cT clinical tumor size, NLR neutrophil lymphocyte ratio, HR hazard ratio, PR progesterone receptor