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Table 6 Univariable and multivariable Cox proportional analyses of clinico-pathological parameters with regard to disease free survival

From: Neutrophil/Lymphocyte ratio has no predictive or prognostic value in breast cancer patients undergoing preoperative systemic therapy

Parameter

Univariable analyses

Multivariable analyses

 

No recurrence

Recurrence

HR (95 % CI)

p value

HR (95 % CI)

p value

Tumor grade

   

0.041

 

0.353

 G1 + G2

69

32

1.00

1.00

 G3

70

52

1.534 (1.017-2.314)

1.278 (0.762-2.142)

PR (biopsy)

   

0.034

 

0.002

 Negative

58

46

1.00

1.00

 Positive

91

43

0.655 (0.443-0.968)

0.448 (0.268-0.748)

cT pretreatment

   

0.001

 

0.002

 cT1 + cT2

100

37

1.00

1.00

 cT3 + cT4

44

49

1.955 (1.309-2.919)

2.244 (1.342-3.750)

pN (tumor)

      

 pN0

72

19

1.00

 

1.00

 

 pN1

60

52

3.255 (1.929-5.492)

<0.001

2.813 (1.440-5.496)

<0.002

 pN2 + pN3

15

18

4.003 (2.057-7.788)

<0.001

6.793 (3.070-15.030)

<0.001

NLR

150

95

0.978 (0.932-1.026)

0.363

1.009 (0.957-1.064)

0.738

  1. Abbreviations: CI confidence interval, cT clinical tumor size, NLR neutrophil lymphocyte ratio, HR hazard ratio, PR progesterone receptor
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