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Table 4 Tentative identification of potential UPLC-MS biomarkers for HCC

From: Serum lipidomic profiling as a useful tool for screening potential biomarkers of hepatitis B-related hepatocellular carcinoma by ultraperformance liquid chromatography–mass spectrometry

RT_m/z Adduct Identified result Main class
1.30_498.8315 [M + H]+ unknown -
1.32_497.5731 [M + H]+ unknown -
1.30_496.6721 [M + H]+ unknown -
4.26_540.4255 [M + H]+ unknown -
3.40_773.5478 [M + H]+ PS(O-16:0/20:2)a Glycerophosphoserines
1.87_534.3902 [M + H]+ unknown -
6.25_369.3538 [M + H]+ unknown -
3.45_822.5670 [M + H]+ PS(O-18:0/22:6)b Glycerophosphoserines
3.59_770.5691 [M + H]+ PC(15:0/20:3)c Glycerophosphocholines
4.23_851.6090 [M + H]+ PI(O-16:0/20:1)d Glycerophosphoinositols
3.99_826.5920 [M + H]+ PS(O-18:0/22:4)e Glycerophosphoserines
  1. a(11Z,14Z); b(4Z,7Z,10Z,13Z,16Z,19Z); c(8Z,11Z,14Z); d(11Z); e(7Z,10Z,13Z,16Z)/22:5(4Z,7Z,10Z,13Z,16Z). TG, triacylglycerol; PS, phosphatidylserine; PC, phosphatidylcholine; PI, phosphatidylinositol; m/z, mass to charge ratio