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Table 4 Tentative identification of potential UPLC-MS biomarkers for HCC

From: Serum lipidomic profiling as a useful tool for screening potential biomarkers of hepatitis B-related hepatocellular carcinoma by ultraperformance liquid chromatography–mass spectrometry

RT_m/z

Adduct

Identified result

Main class

1.30_498.8315

[M + H]+

unknown

-

1.32_497.5731

[M + H]+

unknown

-

1.30_496.6721

[M + H]+

unknown

-

4.26_540.4255

[M + H]+

unknown

-

3.40_773.5478

[M + H]+

PS(O-16:0/20:2)a

Glycerophosphoserines

1.87_534.3902

[M + H]+

unknown

-

6.25_369.3538

[M + H]+

unknown

-

3.45_822.5670

[M + H]+

PS(O-18:0/22:6)b

Glycerophosphoserines

3.59_770.5691

[M + H]+

PC(15:0/20:3)c

Glycerophosphocholines

4.23_851.6090

[M + H]+

PI(O-16:0/20:1)d

Glycerophosphoinositols

3.99_826.5920

[M + H]+

PS(O-18:0/22:4)e

Glycerophosphoserines

  1. a(11Z,14Z); b(4Z,7Z,10Z,13Z,16Z,19Z); c(8Z,11Z,14Z); d(11Z); e(7Z,10Z,13Z,16Z)/22:5(4Z,7Z,10Z,13Z,16Z). TG, triacylglycerol; PS, phosphatidylserine; PC, phosphatidylcholine; PI, phosphatidylinositol; m/z, mass to charge ratio