Table 4 A ROAST gene set test was performed to evaluate whether a specific survival pathway was either up- (â–²) or downregulated (â–¼)
From: Low-power photodynamic therapy induces survival signaling in perihilar cholangiocarcinoma cells
ITL 50 | ITL 500 | ||||
|---|---|---|---|---|---|
Geneset | Genes | Direction | P-value (FDR) | Direction | P-value (FDR) |
AP-1 | 18 | â–² | 0.102 | â–¼ | 0.927 |
NFE2L2 | 13 | â–¼ | <0.001 | â–² | 0.927 |
UPR | 22 | â–¼ | 0.141 | â–¼ | 0.164 |
HIF-1 | 28 | â–² | <0.001 | â–¼ | 0.059 |
NF-κB | 21 | ▲ | <0.001 | ▲ | 0.059 |