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Fig. 3 | BMC Cancer

Fig. 3

From: Silvestrol induces early autophagy and apoptosis in human melanoma cells

Fig. 3

Silvestrol induces transcriptional and translational changes in MDA-MB-435 cells. a Cells were incubated with 3MA (10 mM), silvestrol (25 nM), or both for 24 h. mRNA expression was assessed by qPCR. b Silvestrol induced p62 degradation and LC3-II accumulation. MDA-MB-435 cells were treated with 25 nM silvestrol from 0-24 h and harvested for protein analysis. The data are represented as means ± SEM, * p ≤0.05

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