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Table 1 Half-maximal inhibitory concentration (IC50) values were determined using a cell proliferation assay

From: Potential anti-cancer effect of N-hydroxy-7-(2-naphthylthio) heptanomide (HNHA), a novel histone deacetylase inhibitor, for the treatment of thyroid cancer

Cell line Histopathology Animal Cell proliferation (IC50*) (μM)
    HNHA TSA SAHA
SNU-80 Thyroid: anaplastic Human 2.74 (±0.9)* 4.02 (±1.0) 6.74 (±1.1)
SNU-790 Thyroid: papillary Human 2.32 (±1.0)* 3.91 (±1.2) 5.31 (±1.4)
  1. Each data point denotes the mean of three independent IC50 values calculated from triplicate MTT assays
  2. SD standard deviation
  3. *reflect that were most significantly different between the groups