Fig. 3From: BPIQ, a novel synthetic quinoline derivative, inhibits growth and induces mitochondrial apoptosis of lung cancer cells in vitro and in zebrafish xenograft modelBPIQ induced apoptosis of H1299 cells. a Cells cultured with different concentrations of BPIQ for 24 h were stained with Annexin V/PI to detect externalization of PS from cell membrane. b Quantitative analysis of Annexin V staining. c Quantitative analysis of apoptotic cells. Different letter notations indicate the statistical significance between BPIQ treatment and vehicle (a vs. b and a vs. c indicate the p < 0.005 and p < 0.001, respectively.)Back to article page