Fig. 6
From: RUNX1-Evi-1 fusion gene inhibited differentiation and apoptosis in myelopoiesis: an in vivo study
VPA promoted the G1 arrest and apoptosis in RUNX1-Evi-1 positive cells. The cells of Tg(RE:HSE:EGFP) embryos were sorted with GFP after two days treated by 70 μM VPA. The ratio of S/G2 phase was sharply decreased (94.81 % vs 20.82 %), accompanied with a sub-G1 peak (61.37 %)