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Fig. 1 | BMC Cancer

Fig. 1

From: RUNX1-Evi-1 fusion gene inhibited differentiation and apoptosis in myelopoiesis: an in vivo study

Fig. 1

Schematic structure of wild-type RUNX1, Evi-1 and RUNX1/Evi-1 [30]. Wild-type RUNX1 possesses RHD at the N-terminus and PST region at the C-terminus. In RUNX1/Evi-1, N-terminal RUNX1 sequences are abruptly interrupted at the end of the RHD and followed by almost the entire coding region of Evi-1, including Evi-1 noncoding region, the first zinc finger domain, the second zinc finger domain, and an acidic (acidic amino acid-rich) domain are shown by boxes

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