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Fig. 6 | BMC Cancer

Fig. 6

From: Plantamajoside, a potential anti-tumor herbal medicine inhibits breast cancer growth and pulmonary metastasis by decreasing the activity of matrix metalloproteinase-9 and -2

Fig. 6

PMS inhibited tumor metastasis via decreasing angiogenesis. The complete lungs were fixed after autopsy and the number of lung metastases foci (arrow) was counted (a). b Quantitative analysis of metastases corresponding to the images in a. Paraffin-embedded sections of control or treated lung tissues from mice were analyzed by (c) H&E staining (Scale bar = 100 μm) and analyzed by (d) Ki67 IHC staining(Scale bar = 25 μm). e and f Quantitative analysis of metastases or Ki67 staining corresponding to the images in a and b respectively. Data represent the mean ± S.D. of three independent experiments. g Paraffin-embedded sections of control or treated tumor tissues from mice were analyzed by CD31 IHC staining. Scale bar = 25 μm. h Quantitative analysis of CD31 staining corresponding to the images in g. Data represent the mean ± S.D. of three independent experiments. The ** indicates significance different. The *** indicates extremely significance different

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