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Table 3 RLU/CO and Ct values for concordant and discordant digene HC2 and Roche COBAS results

From: Comparison of the Roche cobas® 4800 and Digene Hybrid Capture® 2 HPV tests for primary cervical cancer screening in the HPV FOCAL trial

 

RLU/CO

Ct (all)

Ct (HPV 16 only)

Ct (HPV 18 only)

Ct (OHR only)

Median (Q1, Q3)

Median (Q1, Q3)

Median (Q1, Q3)

Median (Q1, Q3)

Median (Q1, Q3)

HC2+/COBAS+

54.9 (8.6, 368.4)

30.2 (26.6, 34.2)

29.4 (26.6, 34.2)

30.7 (27.2, 35.0)

30.3 (26.3, 33.8)

HC2+/COBAS−

5.9 (2.7, 16.4)

–

–

–

–

HC2−/COBAS+

0.3 (0.2, 0.5)

38.3 (36.8, 39.1)

39.0 (38.0, 40.0)

38.1 (37.0, 38.8)

38.2 (36.7, 38.9)

HC2−/COBAS−

0.1 (0.1, 0.2)

–

–

–

–

  1. Abbreviations: HC2 Digene Hybrid Capture® 2 high-risk HPV DNA test®, COBAS Roche cobas® 4800 HPV test, RLU/CO relative light unit/cutoff, Ct cycle threshold, Q1 first quartile, Q3 third quartile
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BMC Cancer

ISSN: 1471-2407

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