Fig. 1
From: Resveratrol elicits anti-colorectal cancer effect by activating miR-34c-KITLG in vitro and in vivo
a Twenty-four hr-Res treatment significantly reduced CRC cell viability detected with CCK8 in a dose-dependent manner (12.5 ~ 400 μМ). ** P < 0.01, *** P < 0.001 (b) CRC cell growth was monitored by RTCA for 48 h in the presence of Res or DMSO. Cells treated with Res displayed lower proliferation. c Res induced cell cycle arrest in HT-29 cells (G2/M phase) and HCT-116 cells (G0/G1 phase) analyzed by flow cytometric analysis. *** P < 0.001 (d) Res increased cell apoptosis in CRC cells analyzed by flow cytometric analysis. ** P < 0.01 (e) Soft agar colony formation assay showed that the size and number of colonies in Res-treated CRC cells were reduced. *** P < 0.001 (f) Res inhibited the migratory and invasive capacities of HCT-116 cells monitored by RTCA